EVE Doing single server for decade now it's not that bad. And single server is great solve the problem of choosing the right server to join or ghost towns.
i think its only one server for get out pirate servers lik in wow, it would be a cluster like in eve online.
I think they should at least give it a try. If it doesn't work during alpha/early beta then they should be able to switch it to regional. I do think it would be sad to split the servers. Would love to have a Europe/North America-server at least.
Europe and NA always have their server, so don't worry. I'm more concerned about Asian Countries and Australia.